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Consistent with this hypothesis, transport limitations have also been observed for biotransformation processes converting achiral precursors such as crotonobetaine to L-carnitine using recombinant E

In addition to the link with mitochondrial metabolism, the high turnover of ATP required for Na/K ATPase function has been reported to be tightly coupled to ATP supply arising preferentially from glycolysis 10,11 providing further evidence for a link between cytosolic Na ion homeostasis and metabolism

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Hepatic encephalopathy (HE) is a significant cause of morbidity and mortality in advanced cirrhotic patients [58]