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Dull, brittle fur coat: Changes to skin and fur coat can be a subtle sign that somethings amiss
Front Pharmacol 5:196

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CHIMERA model has also been more recently applied to gyrencephalic ferrets, also reporting axonal injury based on enhanced APP signal, and neurofilament M (RMO) levels, as well as increase in tau phosphorylation AT180 at the base of the sulci by using a higher intensity impact, in turn offering a possible CTE animal simulation (Krieg et al., 2023)

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