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Distributionlevodopa predominantly travels unbound in plasma and enters tissues readily, while polyphenols often bind to albumin or are sequestered within specific tissues [106]

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Traditional pain medications like NSAIDs, opioids, and corticosteroids can provide short-term relief but carry risks including side effects, dependency, and long-term health consequences

10.1016/j.cca.2014.01.007 Clin
