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For example, the steric bulky substituent at ring A on 2c reduced the potency compared to the unsubstituted 2a , this is due to chelating ability towards the copper ions

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Additional research discussions may reference this compound in experimental models focused on inflammation, oxidative stress, antioxidant defense, wound healing, angiogenesis, tissue repair, and damaged tissue remodeling in which enzymes break down older matrix components, as outlined in our educational overview of GHK-Cu research applications

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