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Taken together with our previous work 11 , the current results showed that GS(S) n SG, a type of polysulfides species, are less common in harvested human tissue than GSSG, but might have a stronger anti-oxidative effect

10.1166/jnn.2017.12636 30 BaskaranL.SoundaryaV.GokulM.ManivannanS.RanjithR.KumarP.et al (2024)

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Animal studies show that increasing methionine in the diet slightly increases homocysteine levels

Treatment of HCC cells with ADI-PEG20 downregulates the key enzymes of pyrimidine synthesis in the TCA cycle, carbamoyl phosphate synthetase 2, thymine synthase (TS), aspartate transcarbamylase and dihydrooratase (CAD) and malate dehydrogenase 1 (MDH-1) activities, making tumor cells more susceptible to 5-fluorouracil (5-FU)