nad+ and acetyl l-carnitine Interplay between acetyl‑CoA metabolism in ischemia-induced mitochondrial pathophysiology Impaired nicotinamide adenine dinucleotide (NAD+)
Description
With regard to the claim of a reduced rate of relapse compared to RYDAPT, the applicant stated that a phase 3 trial demonstrated that the cumulative incidence of relapse (CIR) at 2 years was 40% for RYDAPT [119] and in the QUANTUM First trial, the CIR at 2 years was 31.2% for VANFLYTA and 43.3% with placebo

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10.1093/brain/awm095 480 WangJ.LiuW.LuoG.LiZ.ZhaoC.ZhangH.et al (2018a)

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Elfiky, A
