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23 The biological mechanisms underpinning weight lossmediated reductions in BP are well-established, with decreased body fat, notably visceral adipose tissue, associated with numerous antihypertensive effects, including a reduction in arterial stiffness, improved insulin sensitivity, and reduced inflammation

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Psychiatry 94 (9), 681688

Confocal fluorescence analysis of SH-SY5Y cells expressing YFP-ArfGAP1 variants reveals that WT ArfGAP1, and to a greater extent the 3A mutant, mostly co-localize with the GM130-labeled Golgi complex, whereas ArfGAP1-3D adopts a distinct cytoplasmic-like localization (Figure 8A)