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Description
Epitalon treatment significantly decreased frequency of spindle defects and abnormal distribution of cortical granules during aging for 12h and 24h, while increased mitochondrial membrane potential and DNA copy number of mitochondria, thus decreasing apoptosis of oocytes by 24h of in vitro aging

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The tight junction protein occludin and the adherens junction protein alpha-catenin share a common interaction mechanism with ZO-1

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