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Individual response varies substantially based on genetics, body composition, activity level, and dozens of other factors

But if your B12 is high without supplementation , it can be a marker for underlying conditions that require medical evaluation, including liver disease, kidney dysfunction, and certain cancers

Without enough B12, the body can't produce these cells efficiently, leading to megaloblastic anemia, a condition that causes weakness and fatigue

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Deep abdominal fat, which responds well to beta-3 adrenergic stimulation, appears particularly susceptible during combination therapy