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In human neutrophils, reduced gliotoxin acts as a generator of superoxide by inhibiting NADPH oxidase [53]

In PVL patients, oligodendrocyte death is closely associated with iron accumulation, excessive lipid peroxidation, and elevated levels of ROS, MDA, and non-transferrin-bound iron in the CSF (395), providing a compelling rationale for targeting ferroptosis in disease management

After parturition, all animals received initially a diet of 30% concentrate and 70% roughage

Wylie et al., 2012)

Whether or not ergothioneine supplementation (25 mg given three times a week for 52 weeks) may be beneficial in delaying or reversing cognitive decline is the subject of an ongoing clinical trial in elderly individuals with mild cognitive impairment (79)