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[46] supplemented glutamine peptide and carbohydrate or only carbohydrate to soccer players that were submitted to an intermittent exercise on the treadmill, and observed an increase in the time and distance (21% and 22%, respectively) and reduced rate of perceived exertion (RPE) after supplementing with glutamine and carbohydrate compared to the administration of only carbohydrate

Angiotensin II is a hormone that is also involved in increasing blood pressure, alongside an increase in PGF2 that exerts antinatriuretic and vasoconstrictor effects with endothelin production, which is involved in the vascular damage caused by OxS [230,231]

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Chronic stress, poor sleep, and a diet high in processed foods and sugar all generate a massive amount of oxidative stress, forcing the glutathione system to work overtime and potentially become depleted

Acknowledgments Figures were created by the authors using Lovart.ai ( (Nano banana pro model) and, where applicable, elements from BioRender.com