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Exogenous Trx and intracellular Trx combine with MIF to form a complex which affects the MIF-induced inflammatory response

Researchers continue investigating these compounds because of their
Beyond vascular [79,80] and immune functions [81,82,83], NO contributes to central and peripheral sensitization by modulating excitatory neurotransmission and interacting with cyclic GMP pathways [84,85,86]
ACS Appl Bio Mater 4:14701482
