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Although the exact mechanisms by which ketogenic diets exert their effects are not fully known, it is believed that these effects are partially mediated through interactions with the gut microbiome [109,110,111]

Individuals with one or two copies of the genetic variation and low activity of the MTHFR enzyme may present with elevated homocysteine levels, which have been associated with inflammation, heart disease, pregnancy complications, and even miscarriages

Emerging evidence suggests that microglia, as key neuroimmune modulators within the CNS, influence the incidence and progression of cardiovascular diseases, including hypertension, myocardial infarction, and ischemia/reperfusion injury, through mechanisms potentially linked to altered autonomic nervous system activity (Wang M

The availability of vaccines that prevent severe disease, intensive care admission and death are paramount in order to reduce and prevent transmission (294)