first trust select dsip fact sheet PSIP and payment report Source@ Png Bulletin DSIP 10mg - Puratek Peptides

Prescription and administration: Once B12 deficiency is confirmed, GPs prescribe hydroxocobalamin injections according to standardised protocols: Standard loading regimen: 1mg intramuscularly three times weekly for two weeks Neurological involvement: 1mg intramuscularly on alternate days until no further improvement Maintenance therapy: 1mg every three months for life in pernicious anaemia or malabsorption conditions (or every two months if there was neurological involvement) Injections are typically administered by practice nurses at GP surgeries

Absorption occurs within minutes

Bacterial fermentation creates AdoB 12 and MeB 12 , which are converted to cyanocobalamin by the addition of potassium cyanide in the presence of sodium nitrite and heat

Prefilled injections of Methylcobalamin B12 delivered with 30 or more single-use 1" SQ syringes require a valid doctor's prescription

N., Landree, L