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Although it is not a phytocannabinoid, mention should also be given to nabilone (Cesamet ) which is a synthetic chemical analogue of delta-9-THC that is approved in Europe and the USA to control nausea and vomiting caused by chemotherapeutic agents used in the treatment of cancer [60]

10.3390/ijms23052850 [DOI] [PMC free article] [PubMed] [Google Scholar] 135.Fehrer C, Brunauer R, Laschober G, Unterluggauer H, Reitinger S, Kloss F, Glly C, Gassner R, Lepperdinger G (2007) Reduced oxygen tension attenuates differentiation capacity of human mesenchymal stem cells and prolongs their lifespan

Vitamin E has multiple functions in male fertility, such as testosterone biosynthesis and modulation of telomerase activity

Next to pharmacological or NAD + precursor modulators, it is possible to raise NAD + levels through exercise 302,306,307 , however, not all preclinical studies investigating exercise have linked increased NAD + levels to mitochondrial function