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For example, the use of ALDH2 activators may accelerate the detoxification of 4-HNE and reduce cellular damage [130, 147]

These findings suggest that if 5-MIAA can be transported via the circulatory system to the ovarian microenvironment, it may exert similar Nrf2-mediated anti-ferroptotic effects in granulosa cells

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Traditionally recognized for its toxic effects at high concentrations, H 2 S is now known to play crucial roles in various physiological processes, including vasodilation, anti-inflammation, and antioxidation, which are relevant to PH pathogenesis