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Chemical modifications at the 2 position of the ribose Sugar specifically 2-O-methyl (2-O-me), 2-fluoro (2-F), 2-O-methoxyethyl (2-MOE), And 2-O-guanidinopropyl (2-O-GP) have been demonstrated to augment oligonucleotide thermal stability, enhance serum resistance, and maintain or improve gene-silencing efficacy, as evidenced in siRNA studies, including those involving hepatitis B virus models

They include: Beef Fish Poultry Garlic Broccoli Brussels sprouts Kale Cauliflower Spinach Avocado Asparagus Kiwi Strawberry Lemon Orange Like oral supplements, not all glutathione from food reaches the cells because the digestive system metabolizes it

doi: 10.1002/wfs2.1340

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Binds with toxins so they are water-soluble and can be easily expelled from the body through kidneys, intestines and skin