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It's FDA-approved with decades of data behind it

For example, the heart can be affected in some types of LGMD, with weakness of the heart muscle (cardiomyopathy) and/or abnormal transmission of signals that regulate the heartbeat (conduction abnormalities or arrhythmias)

This phenomenon is mechanistically regulated by negative feedback control mediated by the downstream targets CYP1A1 and AHRR [7, 8]

van Os, J., Rutten, B

Mitochondrial supplementation, though safe, fails to improve oocyte competence, with studies reporting no significant changes in embryo development or fertilization rates (Ferreira et al., 2021)
