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Yingfei Xi, Ningbo Second Hospital, China
used matrigel as a mechanical scaffold to achieve robust differentiation of mouse ESCs into ear sensory neurons by individually regulating signaling pathways such as transforming growth factor beta (TGF), bone morphogenetic protein (BMP), and by progressively adding FGF2, BDNF, and NT-3 to mimic important steps of inner ear development [123]
[] The effects of lead exposure on the peripheral nervous system result in peripheral neuropathies, which are demonstrated by diminished motor activity
