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Similarly, after iron repletion, the E3 ubiquitin ligase HERC2 (HECT and RLD domain-containing E3 ubiquitin protein ligase 2) interacts with NCOA4 and induces its proteasomal degradation, rendering HERC2 a negative regulator of ferritinophagy[60]

[DOI] [PMC free article] [PubMed] [Google Scholar] 126.Meng Y., Li T., Zhou G.S., Chen Y., Yu C.H., Pang M.X., Li W., Li Y., Zhang W.Y., Li X

With respect to niacin the designation NAD (and NADP) refers to the chemical backbone of the active form of the vitamin-derived cofactor

10.1186/1476-4598-12-86 77 HouG