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Right-sided congestive heart failure (RS-CHF) causes poor blood return to the heart

Specifically, since a decrease in the Firmicutes/Bacteroidetes (F/B) ratio in the gut is associated with reduced inflammation, Qifeng Gubiao Granules have been shown to decrease the abundance of p:Firmicutes and increase p:Bacteroidetes in the gut of COPD mice, thereby reducing inflammation (123)

[DOI] [PMC free article] [PubMed] [Google Scholar] Sheppard RC

In contrast, other studies have reported an increase in peripheral blood Tfh cell levels (146), especially for those cell subsets expressing activation markers such as PD-1 (166), HLA-DR and CD38 (167)

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