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Cytoprotection by HO-1 against OS results from the generation of three products: carbon monoxide (CO), biliverdin-bilirubin, and ferrous iron (Fe +2 )

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Notably, although the NO system is largely implicated in stomach cytoprotection and colitis lesions[2-4], the application of L-NAME (a vasoconstrictor)[11] and/or L-arginine (a vasodilator)[11] has not been investigated with respect to the immediate presentation of the blood vessels after a segment of left colic artery and vein was occluded by two ligations

however, little is known about how oxidative stress may play a critical role in this condition (Hulsebosch et al., Evidence supports that after a central nervous system injury, increased extracellular glutamate levels activate several intracellular pathways including ROS formation

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