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By hyperactivating the hypothalamic-pituitary-adrenal (HPA) axis, retinoic acid, the active form of vitamin A, has been related to depressed behavior

Bacterial LPS is a common mechanism to stimulate microglia activation of pro-inflammatory cytokine release
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The ratio of reduced glutathione to oxidized glutathione has been documented as a noted factor in many diseases and chronic health issues

Alzheimer's disease: Genes, proteins, and therapy