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doi: 10.1038/s41575-018-0001-1 80 KimD

Targeted delivery to the lymphatics and lymphoid tissues has the potential to improve oral bioavailability, enhance vaccination and tolerance induction, target delivery to lymph-resident cancer metastasis and infection, and promote the utility of treatments for diseases ranging from infections such as HIV to cancer and inflammatory and metabolic disease

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drying time between passes, 10 s

For example, luteolin is effective in therapeutically induced cytotoxicity of cancer cells due to its suppression of cell survival pathways, such as phosphatidylinositol-3-kinase (PI3K)/Akt, NF-B, and X-linked inhibitor of apoptosis protein (XIAP), resulting in the stimulation of apoptosis pathways, including the induction of the p53 tumour suppressor [39]