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Eye smarter than scientists believed: Neural computations in circuits of the retina
Wang LL, Guan L, Hao PL, Du JL, Zhang MX
Over time, insulin resistance can be joined by declining beta-cell function, so the pancreas can no longer meet demand
In addition, ferroptosis is also manifested by a decrease in protein GPX4 levels, the core enzyme that regulates the antioxidant system (glutathione system) (Jiang et al., 2021
These abnormalities occur early in the disease course and progressively worsen over time
