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coli via extracellular activity of DegP
Once glutamine is converted into glutamate by the enzyme GLS, glutamate is able to serve multiple functions in AML cells, such as (1) directly converting to -KG, (2) serving as a nitrogen source following deamination, and (3) regulating the signaling events involved in mTORC1 activity
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doi: 10.1093/carcin/bgr229
