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Patients exploring tesamorelin for body composition often compare it with other peptide therapy options before starting treatment

Its N-terminal trans-3-hexenoic acid modification gives it substantially greater enzymatic stability than native GHRH documented as approximately 49-fold more potent than the endogenous peptide in rat pituitary cell studies

[DOI] [PubMed] [Google Scholar] Ogino T, Kawabata T, et al

In vivo evidence for the effect of MGO on pericytes and the consequence for BBB integrity is limited

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