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As shown in Figure 2, incubation of GSH and OPA at 25 C generated better reactivity but when prolonged, resulted in time-dependent degradation (Figure 3A)

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Bress AP, et al (2024): The Management of Elevated Blood Pressure in the Acute Care Setting: A Scientific Statement From the American Heart Association

Beyond epidemic vaccine, circRNA has also been designed for cancer vaccines to drive immune responses in hard-to-treat malignancies such as immune exclusive tumors and immune desert tumors [110]

2.3 Cisplatin induces mitochondrial dysfunction When cisplatin enters the mitochondria, it acts directly on the inner mitochondrial membrane, leading to the impairment of the function of the electron transport chain, the reduction of ATP production and the induction of ROS generation (Elmorsy et al., 2024), and the inhibition of the efficient antioxidant defence system composed of glutathione (GSH) and enzymes, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx), in the interstitial space of the mitochondrial membrane