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The knowledge about the role of important biomolecular variations may provide a valuable opportunity not only for the early detection of CAD based on the specific gut microbiota patterns (which in turn affect plasma biomolecules compositions) but also for developing novel therapeutic approaches based on the manipulation of gut microbiota using oral nanotechnologies

Thus, the radical scavenging capacity of low-molecular-weight antioxidants in an intracellular environment is negligible compared to the ROS scavenging/converting capacity of antioxidant enzymes

While l-theanine exhibits a good safety profile based on toxicology studies, caution is warranted regarding the purported health benefits, until stronger scientific substantiation emerges