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In reproductive stress diseases, for example, endometriosis, increased expression of NF-B has been confirmed in cultured endometriotic stromal cells [105] and peritoneal macrophages isolated from women with endometriomas [106]

(2002) Journal of Biological Chemistry

BDNF knockdown experiments further cement its role: mice with conditional BDNF deletion in the ventral tegmental area (VTA) or hippocampus develop spontaneous depressive phenotypes, even in the absence of ethanol, while BDNF infusion into these regions rescues ethanol-induced anhedonia (Zhong et al
