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The blunted inhibition of hexokinase by glucose-6-phosphate is important not only for allowing high rates of upstream glycolysis and ensuring avid glucose uptake from the extracellular space, but also because glucose-6-phosphate may originate from galactose (through glucose-1-phosphate), glycogen (through glycophagy and/or glycogenolysis), and ribose (through the pentose phosphate pathway forming fructose-6-phosphate), (Fig

SOD catalyzes the conversion of superoxide radicals into hydrogen peroxide, which is then further detoxified by catalase and glutathione peroxidase

On rare occasions, the potential side effects of increased gas, loose stools, flushing, and weight gain have been reported

doi: 10.1016/j.apt.2017.11.003 41 ChakravartyA.AhmadI.SinghP.Ud Din SheikhM.AalamG.SagadevanS.et al

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