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(2020) Local administration of methylcobalamin for subacute ophthalmic herpetic neuralgia: a randomized, phase III clinical trial

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Gut 55 , 342347 (2006)

Animal studies show substantial evidence across stroke models (full functional recovery in spatial memory, motor coordination, balance), Parkinsons models (protection of dopaminergic neurons, near-complete prevention of mortality), multiple sclerosis models (significantly less brain damage), and traumatic brain injury (reduced hemorrhage and edema)