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patients treated with NAC (600 mg in the feeding tube) twice daily developed significantly less clinically confirmed pneumonia compared with patients that received placebo (26.6 % vs

6 Both pathways highlight ROS as key initiators of NETosis

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Regulatory role of mitochondria in ferroptosis Mitochondria, semi-autonomous organelles, have unique metabolic mechanisms that allow these organelles to resist ferroptosis [50, 51]