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With exogenous GH, in-vitro proliferation markers increased and JAK2 was activatedsuggesting a permissive/synergistic interface with GH signaling in this cell type
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And thus threatened the lucrative business market that big pharma had created
Researchers opting for the 8mg maintenance dose would reach it at week 16, and the 4mg dose after just 4 weeks on the escalation schedule
