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One landmark study in the Journal of Lipid Research demonstrated that even with identical hazard ratios on average, apoB pointed to higher risk in a meaningful subset of individuals where non-HDL underestimated the burden

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[158] found increased activity of choline acetyltransferase and expression of nerve growth factor (NGF) receptor in the striatum, and increased NGF protein levels in the hippocampus of rat pups after intracerebroventricular injection of ALCAR every other day from 021 days of age