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Methodology and mechanism

However, there may be slight risks associated with certain methods, such as skin irritation, redness, or temporary pigment changes

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Mohammad CA, Ali KM, Sha AM, Gul SS (2023) Effect of Curcumin gel on inflammatory and anti-inflammatory biomarkers in experimental induced periodontitis in rats: a biochemical and immunological study

In terms of side effects and tolerability, the advantage goes to neither (comparable)