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Rizzardi N, Liparulo I, Antonelli G, Orsini F, Riva A, Bergamini C, et al

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Concurrently, ER can induce autophagy independently of classical pathways (mTOR, PI3KCIII, MAPK) via regulators such as BAG3, ATG7, and WIPI, while ER modulates autophagy in a context-dependent manner, influencing autolysosome formation, cyclin degradation, HIF function, and interacting with autophagy-related proteins (ULK1, BECN1, LC3B, ATG16L1, p62) and the NLRP6 inflammasome