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The following experiments further confirmed this hypothesis as inhibition of ferroptosis with Fer-1 abolished the anti-cancer role of APS and DB, with enhanced cell proliferation, migration, invasion and tumorigenesis in vivo and weakened cell apoptosis, whereas the liver injury did not change

258 Kidney injury markers clusterin and cystatin c significantly decreased in the methionine restriction (MR) mouse injury model

However, patients with excessive toxicity should be extremely careful with self-treatment

PMID: 18796312

[68,69] This effect of GSH on skin pigmentation was reported half a century ago, with black human skin shown to exhibit lower levels of GSH than white skin