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The severity of colon mucosal damage was evaluated using the colonic mucosal damage index (CMDI) following the criteria outlined by Jiang et al

Specifically, studies have shown that the loss of mTOR-dependent autophagy pathways impairs synaptic pruning which further underscores immune dysregulation as a contributor to the development of ASD [8,9]

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For example, during the fasted state, the liver, skeletal muscle, and many other organs and tissues rely primarily on fatty acid oxidation for energy