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In endurance events, where glycogen depletion is a limiting factor, maximizing fat utilization can provide a more sustainable energy source, potentially delaying fatigue

LC serves as an intra-mitochondrial vehicle for the acyl group, which in the form of acyl-CoA acts as a substrate for the oxidation process, producing energy for sperm respiration and motility [7, 8]

4.4 Neonatal hypoxicischemic encephalopathy The pathophysiology of HIE involves hypoxicischemic injury, characterized by perturbations in mitochondrial dynamics and the inhibition of critical energy-producing pathways, including oxidative phosphorylation and fatty acid -oxidation ( -oxidation and its prior neuroprotective effects in adult ischemia models, it represents a biologically plausible candidate for investigation in neonatal brain injury

Individuals with heterozygous mutations are asymptomatic carriers with no clinical consequences