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Researchers drew on data from more than 86,000 healthy older adults enrolled in the UK Biobank and ASPREE studies

Cellular deconvolution of bulk transcriptomic data from the peri-infarct cortex showed that cells with molecular signature similar to the so-called disease-associated astrocytes, originally described in the vicinity of -amyloid plaques in a mouse model of AD and in the aged brain 464 , are present also in post-stroke tissue 383

After one IV iron infusion, her ferritin rose to 50 g/L and hemoglobin went from 110 to 125 g/L within 6 weeks

Their primary mechanism involves enhancing descending inhibitory pathways from the brainstem to the spinal cord
