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Chronic sleep deprivation can significantly deplete your levels

Cyclin E, for example, is degraded by the SCF ubiquitin ligase complex, which uses the F-box protein Fbw7 to recognize and ubiquitinate cyclin E

Skin color is determined by melanin production

8 , e2655 (2017)

doi: 10.1191/0961203304lu1020oa
