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Unlike collagen, which primarily provides structural support, glutathione focuses on cellular protection and detoxification

10.1038/s41598-020-69296-1 Sci Rep

Caviness Distinguished Professor of Medicine at the University of North Carolina School of Medicine

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Possibly, this toxicity, in addition to lower esophageal sphincter and pyloric sphincter failure, involves sole NSAIDs-gastric ulcers, presenting with aspirin (and thereby, aspirin was used intragastrically) (14) and ibuprofen (10), as well as with those agents combining gastric and small intestine ulcers (i.e., diclofenac (9, 11))