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This gene variation negatively impacts carnitine transport across the blood-brain barrier (in males and not females), preventing the synthesis of a carnitine precursor called trimethyllysine
This makes injectable L-Carnitine especially effective during physical activity, when your body is primed to tap into stored fat
doi:10.3945/ajcn.113.062802
If you adhere to a plant-based diet, it's quite possible you'll see greater benefits from carnitine supplementation than omnivores will
