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Raychaudhuri B, Han Y, Lu T, Vogelbaum MA

Inability of plasmacytoid dendritic cells to directly lyse HIV-infected autologous CD4+ T cells despite induction of tumor necrosis factor-related apoptosis-inducing ligand

The outcome of fetal interactions with agents potentially teratogenic for the nervous system depends on the species and age of the fetus and the nature of the agent

Think of it as potentially lowering the background noise of inflammation rather than silencing the specific alarm signals that drive autoimmune attacks

A new review by Sebastin Zagmutt Caroca PhD, Biotechnology Rosalia Rodriguez Rodriguez et al proposes a compelling framework positioning chronic hypothalamic microinflammation as an initiating eventnot a downstream consequenceof systemic metabolic dysfunction and #obesity