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Description
Instead of targeting TAAs, UniCARs are engineered to recognize the human peptide sequence E5B9, also known as the UniCAR epitope, which is a fragment of the human nuclear autoantigen La/SS-B and absent in living cells (Jureczek et al., 2019)
Nature 360: 467-471
Alternative volumes for different resulting concentrations Rule: For AOD-9604 we recommend 2 ml as the optimal compromise volume
Additionally, mitochondrial DNA mutations and reduced mitophagy exacerbate mitochondrial dysfunction and contribute to the progression of AD [158]
Matel, JL
