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Genome-wide association studies and clinical investigations have established a link between the MTHFR C677T polymorphism and a heightened susceptibility to hypertension and hypertension in pregnancy, with a potential increase in risk of up to 87% [98]
Sci 9 (5) (2018) 11731183
Beyond the traditional AMP/ADP-dependent mechanisms, AMPK can be activated through alternative pathways
Tumoral EPAS1 (HIF2A) mutations explain sporadic pheochromocytoma and paraganglioma in the absence of erythrocytosis
