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It was also identified that in the identical subfamily the motif distribution of members was extremely conservative, such as subfamily I members had motifs 7,3 1,8, 2, 5, 4, 10, and 6
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[5] Clinical significance [edit] Reactive electrophiles produced by oxidative metabolism have been linked to a number of degenerative diseases including Parkinson's disease, Alzheimer's disease, cataract formation, and atherosclerosis hence reduced expression of the GSTA4 enzyme may have pathophysiological consequences

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