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In the last decades, IGF-1 has been implicated in many physiological actions, among others: tissue growth and development, proliferative, lipid metabolism, pro-survival/anti-aging, anti-inflammatory, anabolic, and antioxidant with neuro- and hepatoprotective properties [105116]
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This study examined the antidepressant-like effects of SILY and SILY/SERT combination in mice to ascertain the role of SILY either alone or as an adjunct to SERT in mitigating DEX-induced behavioural and morphological changes in mice
