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To enhance therapeutic precision and minimize unintended effects, future studies should explore targeted delivery methods or utilize cell-specific genetic tools to dissect irisins mechanisms of action more accurately

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Second, mPEG- d -PEI was obtained by the conjugation of mPEG-CHO and PEI through a Schiff base reaction in neutral, aqueous solution
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Culturing hepatocytes in choline and methionine-deficient media impaired VLDL secretion
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doi: 10.1007/s13277-014-2924-7 35 ShimizuWTsuchiokaYKarakawaSNagataKMukaiJYamagataTet al
